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TargetMol
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Selleck Chemicals
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Bio-Techne corporation
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N/A
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CI-1033 is a potent, irreversible ATP binding site–directed pan-ErbB tyrosine kinase inhibitor with IC50 in the low nanomolar range for EGFR, HER2, and ErbB-4.
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N/A
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Inhibitor of EGFR, HER2 and HER4 tyrosine kinases. Inhibitor of EGFR, HER2 and HER4 tyrosine kinases.
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N/A
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Canertinib Dihydrochloride is a water-soluble, EGFR tyrosine kinase inhibitor. It induces ErbB-independent apoptosis in human leukemia (HL-60 and U937) cells in vitro. It also irreversibly binds ATP binding sites which are directed by pan-ErbB tyrosine
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Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their
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Image Search Results
Journal: STAR Protocols
Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform
doi: 10.1016/j.xpro.2025.104250
Figure Lengend Snippet:
Article Snippet:
Techniques: Recombinant, Membrane, Software, Imaging